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Li\u00e8ge, Belgium – April 1, 2024 \u2013 CMD-COAT<\/a><\/strong>, a leading research and development company, and FRESCI<\/a><\/strong>, experts in health innovation, are proud to announce the launch of Coati-X, a groundbreaking project funded by the European Innovation Council<\/strong> to deliver a proprietary bioactive coating technology designed to enhance the safety and effectiveness of intravenous catheters and implantable medical devices. This new generation of coatings aims to prevent two major complications: infections and thrombosis.<\/strong><\/p>\n\n\n\n Intravenous catheters and implantable medical devices are essential tools in modern healthcare, but they come with significant risks. Catheter-related bloodstream infections and thrombosis are major causes of patient morbidity and mortality, leading to prolonged hospital stays and increased healthcare costs. CMD-COAT addresses these challenges by offering a coating that combines anti-thrombotic, anti-microbial, hydrosoluble, and biocompatible properties.<\/p>\n\n\n\n CMD-COAT employs a unique layer-by-layer assembly of cross-linked nanogels that can be loaded with anti-thrombotic and antibiotic drugs. This innovative design allows for controlled, localized release of bioactive agents, significantly enhancing the coating’s duration of effectiveness. The nanoreservoirs created by these nanogels can entrap multiple bioactive molecules, combining several biological activities in a single coating. This technology is adaptable to various biomaterials, including metallic, biological, and polymeric surfaces.<\/p>\n\n\n\n CMD-COAT leads a consortium that brings together top researchers, cardiovascular specialists, biologists, chemists, and FRESCI business strategists. Together, they aim to accelerate the development and validation of this coating technology, bringing this innovative solution to market readiness.<\/p>\n\n\n\n The first applications of Coati-X will focus on central venous catheters (CVCs) and peripherally inserted central catheters, which are commonly used in medical practice and associated with high risks of infection and thrombosis. CMD-COAT is going to partner with major medical device manufacturers to leverage their production capabilities, regulatory experience, and distribution networks.<\/p>\n\n\n\n CMD-COAT holds several patents for the Coati-X technology and its applications. The company plans to file additional patents and trademarks to expand its intellectual property portfolio. Future developments during the Coati-X project include adapting the technology for other cardiovascular devices such as stents, heart valves and pacemakers.<\/p>\n\n\n\n “Our mission at CMD-COAT is to revolutionize the safety and effectiveness of medical devices through innovative coating technologies,” said Professor Patrizio Lancellotti, Head of the Cardiology Department at Li\u00e8ge University Hospital and co-founder of CMD-COAT. “Coati-X represents a significant advancement in preventing the two most frequent and severe complications associated with medical devices.”<\/p>\n\n\n\n <\/p>\n\n\n\n FRESCI<\/strong> by SCIENCE&STRATEGY SL is dedicated to enhancing the impact of research in human health through strategic consultancy and evidence-based solutions. Specializing in strategic and organizational development, research and analysis, funding and financial planning, and stakeholder engagement, FRESCI supports organizations across public, private, and philanthropic sectors. By amplifying the value of research results, FRESCI aims to foster reproducibility, sustainability, and innovation in science, business, and regulation.<\/p>\n\n\n\nInnovative Technology to Address Critical Medical Needs<\/h3>\n\n\n\n
Four Key Technical Features of CMD-COAT Solution:<\/h3>\n\n\n\n
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Innovative Cross-Linked Nanogels<\/h3>\n\n\n\n
Project Consortium and Market Strategy<\/h3>\n\n\n\n
Market Potential and Strategic Partnerships<\/h3>\n\n\n\n
Intellectual Property and Future Developments<\/h3>\n\n\n\n
CMD-COAT’s Commitment to Innovation<\/h3>\n\n\n\n
About FRESCI<\/h3>\n\n\n\n